General Catalyst Institute
The General Catalyst Institute (GCI) bridges venture capital and government to promote national resilience through transformative technologies.
Overview
Led by Founding CEO Teresa Carlson, GCI partners with policymakers and startups to shape policies in AI, healthcare, defense, manufacturing, and energy.
Introducing the GC Institute
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Introducing the GC Institute
GCI Report
U.S. Resilient Defense
A new strategic framework for accelerating how the defense enterprise gets innovation into the hands of warfighters. The report outlines ten concrete actions to drive speed, adaptability, and rigorous operational validation as the foundation of credible deterrence.

GCI Report
U.S. Healthcare that works
GCI has launched a whitepaper on priority U.S. healthcare issues ripe for modernization and the urgent need to improve policy to deliver high-quality value-based care. The paper unveils Catalyzing Care: A Framework for a Healthier America to help transform healthcare delivery.

Insights
The summit on u.s. resilience
Our flagship policy summit convening founders, investors, policymakers and the media to discuss ways to help startups thrive while strengthening America's resilience.
Featured Press
Statements & COmments
On Health
On February 23, 2026, GCI submitted comments to a U.S. HHS Department request for information on accelerating AI adoption in clinical care.
On Fintech
On February 20, 2026, GCI submitted comments to the UK's Financial Conduct Authority on cryptoasset proposed rules and guidance.
On Health
On January 17, 2026, GCI submitted a response to the FDA's information request on how venture firms and portfolio companies can better access agency contracts and task orders.
On Artificial Intelligence
In December 2025, GCI partnered with the Middle East Institute on a report exploring how best to create a GCC AI stack.
On Health
On December 19, 2025 GCI submitted a response to a White House information request in coordination with Transfyr, a GC portfolio company.
On Financial Innovation
On December 19, 2025 GCI submitted a response to a White House information request in coordination with Transfyr, a GC portfolio company.
On Energy
On November 6, 2025, GCI endorsed the SPEED Act (H.R. 4776) in the U.S. House which would streamline the permitting process for energy projects.
On Artificial Intelligence
On October 27, 2025, GCI submitted a response to the White House's information request on AI regulatory reform.
On Manufacturing
On September 30, 2025, GCI submitted views regarding a proposed U.S. National Strategic Plan for Advanced Manufacturing.
On Fintech
On August 4, 2025, GCI submitted our recommendations to the U.S. Senate Banking Committee on establishing a digital asset market structure framework.
On Artificial IntelligenceOn Fintech
In July 2025, GCI conducted the first comprehensive mapping and analysis of all EU AI Act standards with recommendations for startup suitability.
On Improving Healthcare
On June 15, 2025, GCI submitted comments to a U.S. Centers for Medicare & Medicaid Services request for information on how to improve the health technology ecosystem.
On Artificial Intelligence
On May 21, 2025, GC Managing Director Marc Bhargava testified at a U.S. House Energy & Commerce Subcommittee on Commerce, Manufacturing, and Trade hearing on AI regulation and the future of U.S. leadership.
On Artificial Intelligence
On March 14, 2025, GCI submitted a letter to the White House outlining policy recommendations of importance to founders and startups as the Trump Administration crafts its inaugural AI Action Plan.
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